Lead Optimization

Hit and lead discovery for any targets Provide the name of the target, and we give you patentable NCEs and core structures within 2-3 months! Besides using the latest label-free technologies for in-house screening programmes, Avidin provides the following SERVICES: Real-time measurements of the cytotoxic effects of small molecules/mixtures/extracts on primary cells or cancer cells in a medium high throughput …

Library Preparation

For in-house and fee for service projects Avidin prepares chemical libraries for hit discovery and lead optimization.

Medicinal chemistry

Avidin’s Chemical Department develops novel chemical synthetic routes to prepare NCEs for the improvement of Avidin’s small molecule collection. For in-house and fee for service projects Avidin performs lead optimization , and focused library synthesis. The laboratory is equipped with the following instruments: ANALYTICAL CHEMISTRY PURIFICATION: COMBIFLASH Rf SYSTEM Rapid and excellent purification of reaction mixture Purification of gramm scales …